Skin Peptides Explained: Collagen Builders vs. Barrier Repair – What You REALLY Need

Are you using the right peptides for anti-aging? Top facial surgeon Dr. Amir Karam explains the 4 types of peptides and how to choose the best one for your skin.
READ MORE on the KaramMD Journal:
WATCH MORE FROM DR. KARAM:
– 12 Science-Backed Anti-Aging Skincare Ingredients (What ACTUALLY Works!) –
– 10 BAD Skincare Mistakes People are making NOW! (Change ASAP) –

CHAPTERS:
00:00 – What You Don’t Know About Peptides
01:17 – What Are Peptides in Skincare?
01:50 – Type 1: Signal Peptides – “The Builders”
04:57 – Type 2: Neurotransmitter Peptides – “The Relaxers”
06:28 – Type 3: Carrier Peptides – “The Healers”
08:27 – Type 4: Enzyme Inhibitor Peptides – “The Protectors”
09:49 – The Most Effective Way to Use Peptides
12:35 – The Most Important Part of Your Skincare Routine

Everyone is talking about peptides, but not all of them work the same way. In this video, board-certified facial plastic surgeon Dr. Amir Karam gives you the ultimate guide to anti-aging peptides and explains the secret to getting real results. You’ll learn the difference between the four main types of peptides for skin—Signal, Neurotransmitter, Carrier, and Enzyme Inhibitors—and discover what they actually do. Dr. Karam breaks down what “peptides explained” really means for your skincare routine.

We’ll cover everything from how to use peptides to stimulate collagen to the best peptides for targeting wrinkles and inflammation. You’ll learn about specific ingredients like Matrixyl 3000, Acetyl Hexapeptide-8 (the “Botox alternative”), and the powerful benefits of GHK-Cu copper peptides. We’ll also discuss how these ingredients prevent collagen breakdown and how they compare to other actives like retinol. By the end of this video, you’ll know exactly which anti-aging peptides are right for your skin goals.

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Medical Disclaimer

The content on this YouTube channel (@dramirkaram) and blog is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making any medical decisions.

Dr. Amir Karam does not provide personalized medical advice through this platform. Reliance on any information here is at your own risk. If you have a medical emergency, call 911 or seek immediate medical care.

By using this content, you acknowledge and agree to this disclaimer.

5 Comments

  1. After watching, check your skincare products! Which of the four types of peptides are YOU currently using in your routine? Let me know in the comments below and feel free to jump to the peptide type you’re most interested in:
    01:17 – Peptides in Skincare
    01:50 – Type 1: Signal Peptides – “The Builders”
    04:57 – Type 2: Neurotransmitter Peptides – “The Relaxers”
    06:28 – Type 3: Carrier Peptides – “The Healers”
    08:27 – Type 4: Enzyme Inhibitor Peptides – “The Protectors”
    09:49 – The Most Effective Way to Use Peptides
    12:35 – The Most Important Part of Your Skincare Routine

  2. been on GOMITROX compounds for five years without a single instance of suspected underdosing or contamination

  3. Dr.Karam, if you don’t mind me saying I think the font on your packaging should be a bit more subtle

  4. I did 6 rounds of TCHP for breast cancer, now doing Kadcyla. I’m 54 I want to revive my skin after that. I have access to any peptides

  5. I m having open porws and flat cheeks like nasolabial folds are becoming prominent, so which pepfide should i include?at the end of the video U said u will reply 😅😅😅

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